Concise One-Pot Multicomponent Reaction Approach to Monofluorinated Spiro-pyrazole-pyridine Derivatives without Additional Catalyst
نویسندگان
چکیده
Abstract Monofluorinated bis-heterocyclic spirocycles: functionalized ethyl 9-fluoro-8-methyl-1,4-dioxo-2,3,6,10-tetraphenyl-2,3,7-triazaspiro[4.5]dec-7-ene-9-carboxylate derivatives were efficiently synthesized from readily available 1,2-diphenylpyrazolidine-3,5-dione, 2-fluoroacetoacetate, aromatic aldehydes, and ammonium acetate via one-pot four-component reactions in the absence of additional catalyst. In protocols, serves not only as fourth component but also
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ژورنال
عنوان ژورنال: SynOpen
سال: 2022
ISSN: ['2509-9396']
DOI: https://doi.org/10.1055/a-1866-4653